Iuka puker Share definition Flag An Iuka puker is a redneck from northern Mississippi who is suffering the ill effects from drinking cheap booze. Billy-Bob threw up in his girlfriend's lap. He's a quintessinal Iuka puker. Iuka puker by Cranberry Bob November 28, 2019 0 0 Get merch Get the Iuka puker mug. Buy Now — $32.95 See more merch