Heffer-mae Share definition Flag A Plus-Size African-American woman who thinks the world revolves around her. This heffer-mae just made a huge commotion and backed the drive-thru line at McDonald's. Heffer-mae by MICHAELANGELODINGO June 18, 2011 0 0 Get merch Get the Heffer-mae mug. Buy Now — $32.95 See more merch