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Laughing uncontrollably, sometimes for hours on end. Often results in the person pissing their pants, and or soiling themselves. It is considered a disease by certain countries, with no cure in sight.

First case was discovered in a small town known as Marshfield
Byron: Oh no, I think Maria has the gunkles.

Markie: Oh god, somebody get some air sanitizer and some toilet paper!
Gunkles by Michael Shmidt March 30, 2009
A fat teenager that crushes chairs and couches and has no regard for doing so, a gunkle also breaks personal items that is given to him to hold they normally have names such as (joe, Kenny, hilda, Charlie, Nolan, Garry, Gertrude.)
That kid is a gunkles for being fat
Gunkles by Phypoo June 11, 2019
gay uncle; an uncle that is gay.
I love my Gunkle Mark and my Gunkle Ed!
gunkle by lzybrunette April 24, 2010

Gunklesnizer 

a gunklesnizer is a word that only the creators will know the true meaning. This will be a urban laegend forever
your such a gunklesnizer!

ganklesaurus funkle 

a prefix to something that is funky, crooked, twisted, stained, malformed, repulsive, odorous, inappropriate, alarming, calloused, disturbing,
I hate when old men wear sandals and let their "ganklesaurus funkletoes" show!

If you do not brush your teeth and floss regularly you could end up with "ganklesaurus funkleteeth"

The last thing anyone wants to see is some nasty woman's "ganklesaurus funklebutt" hanging out of the bottom of a too short skirt
A very large, thought to be mythical beast, that roams the open land at Whiting Field in search of Barbeque Suace from Whataburger, not the stuff they give anyone but the good stuff the make and keep in the back and charge $.37 for. Treat gunkles the same way you would treat Gremlins. Gunkles have many predators, although the main predator is a squirrel.
The gunkle was unable to concentrate on his next move because the squirrels kept interupting him. OR. The gunkle train of thought was clouded due to the fact that Barbeque sauce was in short supply!
gunkle by squirrel superhero May 23, 2010