Go Large Marge on a mother fucker Share definition Flag The act of extremely flipping out on someone. If people don't quit telling me what to do today, I'm going to go Large Marge on a mother fucker. Go Large Marge on a mother fucker by chayen August 4, 2009 0 0 Get merch Get the Go Large Marge on a mother fucker mug. Buy Now — $32.95 See more merch