D.S 

To get real real drunk and jump into a canal during the day. To get hopped up on pudding and bud lite and jump into body of water

yo! did you hear about Dave. He was having some bud lights at scotty's and decide to do a D.S

D.S by Sharkton January 26, 2011

D.S 

A term that originated and was popularized in Sudbury, Ontario. Short for Down Syndrome, it is used in a less offensive way or when it would be otherwise inappropriate, ie in public. Used as a remark on the general stupidity of someone/something or a recent event.

Guy 1 : Man, Dave is really pissing me off today!

Guy 2 : Why? What did he do?

Guy 1 : He's just being a D.S and it's really annoying.

Bob: Did you see what Liam did at the party last night?

Mark: Oh my god I know dude sooo fucking D.S

Guy: Fuck! I've been trying to open this jar for ten minutes, this is so D.S !

D.S by the-chiefs April 29, 2016

D.S 

Acronym for "Daily Shit". A D.S is penetrating feces out of your anus daily.

Damn bro, I wish I could D.S like Sabrina Marie Wilkerson.

D.S by Sab123123 November 4, 2010

D.S 

Dick Stopper (Known as a girl with a big nose). Her nose stops her from deepthroating a dudes penis fully.

No D.S's here!

D.S by s k a t e May 27, 2011

D.S 

Dog Shit

Man Look At Ur Initials....D.S.... They Stand For Dog Shit!!

D.S by XxNovacaineXx February 2, 2009

d.s 

short for down sindrome which some fool shortened to d.o but still it stands for the result of having a really ugly person

that girl has down sindrome

d.s by thug#1 July 13, 2003

D's 

short for Dayton rims

homie1: Damn nigga, look at that 64' on D's
homie2: Aw shit! im bout to hit a mothafuckin lick on that nigga

D's by Avin May 13, 2005