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Crusty and Ankles being compounded into one word.

Somebody with a unusual amount of crust on their ankles.
Eww look at Theleah she has crankles!
by Rofllollololol December 22, 2010
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3
Crankles: unusually skinny, bony ankles, which in comination with other observable traits, may indicate habitual use of methampetamine, also known as crank. A "crank skank", for example, would likely have crankles. Derived from the term "cankles" - its opposite.
"Check out the crankles on that ho!; bet she'll fuck me for this fuckin' phat rail!"
by Gemilie August 14, 2006
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4
The condition which usually afflicts large ladies where the ankle and calf are nearly the same diameter
check out the crankles on that bloater
by darkman69 September 13, 2008
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5
A person that gets inured easily, and constantly hurts themselves.
"I landed on my ankle playing basketball today."
"Yo, you're such a crankle!"
by coolest person April 20, 2008
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7
A crack or pop of the ankle.
Adi was getting up from the sofa in a twisty way and cracked her ankle multiple times --crankle(s)
by Mo21 June 05, 2016
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