The area in affected female legs where the calf meets the foot in an abrupt, nontapering terminus; medical cause: adipose tissue surrounding the soleus tendon, probably congenital, worsened by weight gain and improved in appearance only by boots. From the English "calf" meaning wide portion of the lower leg, and "ankle" meaning slender joint of leg with foot.

Briefly, "the realization that each random passerby is living a life as vivid and complex as your own." Originally from the Dictionary of Obscure Sorrows, which has a lot more beautiful neologism definitions like this you might enjoy.

Noun. A sight common among the morbidly obese. The point at which one is so obese that there is no thinning of the leg between the calf and the ankle, which creates a sense of fusion between the two. Consequently "Cankle" comes from the fusion of CAlf and aNKLE.

A swelling of the ankle and lower calf so as to obliterate the normal tapered boundary between the two. While it may be simply be deposition of adipose tissue (fat), or even excessive standing, in some cases the cankle may represent a symptom of kidney disease or even congestive heart failure, in that the swelling could be caused by excessive fluid retention in the lower leg which the failing heart is unable to pump uphill or the kidneys are unable to excrete into the urine.

While the term is ordinarily used in a sexist manner to insult a woman's beauty, cankles may represent more than a mere cosmetic problem, but actually a dangerous situation calling for evfaluation by a physician.

The absence of a defined ankle on a person - whereby the calf of the leg merges directly into the foot. The calf appears to replace the ankle - hence the term "cankle".

Also known as “peasant ankles” for the ostensible stability and hardiness afforded by the wide, steady base of the legs, which aids in long hours of tillage and harvesting. As such, the condition is most prominent in women of Russian or Italian ancestry.
It is the condition where the ankle girth is equal to or indiscernibly less than the girth of the widest part of the calf. It is not ankle fat per se, but rather a state of being “big-boned” in the ankle region while simultaneously experiencing gross muscle atrophy of the gastrocnemius.
Symptoms include: deep elastic grooves from socks, increased razor wear-and-tear, ability to reap 20 bushels of grain per hour.

n. 1) An aesthetically unfortunate physiological condition which leaves its victims with no discernable narrowing of the ankle between the calf and the foot. 2) An ankle which has no discernable narrowing from the calf to the foot. History: The word is derived a combination of the words calf and ankle. Victims of this condition are advised to avoid the following: ankle boots, ankle-strap shoes, anklets, ankle socks, ankle tattoos, high-top shoes, and any other footwear or legwear that might draw attention to the cankle region.