When a woman obsesses over a man while he's deployed overseas because she's in love with the idea of him, but when he returns home she becomes immediately disinterested in him. So-named for Channing Tatim's role as a gay soldier in "Dear John".
"Dude we go home tomorrow, and Heather just stopped talking to me."
"Dude I knew it. That bitch has got Channing Tatum Syndrome."
"Dude I knew it. That bitch has got Channing Tatum Syndrome."
by LouisColling October 4, 2011
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