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An interjection shouted out after a person experiences an excrutiatingly painful burn, or insult. The "Ch-ch" noise refers to the sound of the cocking of a shotgun. The "burn!" replaces the sound of "bang!". That's how painful this particular burn must have been.
Boy: I don't know why you wear a bra. It's not like you have anything to fill it.
Girl: And yet you still wear pants.
Random friend: Ch-Ch-BURN!!!
by MentalFloss December 29, 2009
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