CUSE

A University of athletic excellence in upstate New York.

CUSE is in the house, OH MY GOD

by Matt Donovan May 13, 2005

CUSE

the ultimate burn ... burn to the MAX

dude, he shizzled your nizzle, thats a top dawg CUSE

by batman --> i mean vanessa May 16, 2003

CUSE

to make some one feel bad

you look like a dog
you a ugly ho

by valiant williams September 08, 2003

CUSE

Short for "because".

I'm going to the mall cuse I need some shit.

by Jigga Spice August 16, 2003

The Cuse

The city of Syracuse, New York.

Nick name used by Syracuse natives when referencing their hometown and/or Syracuse University.

Did you watch the Cuse game last night?

by John Stamos April 03, 2005

Cuse

Familiar, endearing name for Syracuse, NY. Used by people of Upstate, New York.

It's snowing in Cuse again.

by Valery Drake May 13, 2005

Cuse

female orifice

Man, she has one fine cuse!

by JamesJJammer January 20, 2012