a sister who is also a best friend, or a friend who is closer to you than a friend and is more like a sister.
My sister, Kim, is also my best friend; she is my sister-biffle!
I love my friend Kristin so much, we are such good friends that she is more like a sister to me; she is my sister-biffle!
I love my friend Kristin so much, we are such good friends that she is more like a sister to me; she is my sister-biffle!
by BAD1484 May 13, 2010

by emilydawsonx June 21, 2011

Best friends for life forever, when "best friends for life" and "best friends forever" are not enough
"We're not just friends, we're not just best friends, we're not just biffles, we're BIFFLES FORIFFLES."
by Mr. La-Liffle June 25, 2009

A girl that has a big booty along with a cute face and rocking body that can show you the time of your life anywhere and anyway she wants to.
by jay em ay January 1, 2009

Came from the word Best Friend. Was Welcomed into the Hip Hop scene by hip hop artist, when the shizzles and the dizzles were popular. est. 1999-2006 ex. Then Mutated into Biff for example; Whats up Biff?
by Daniel D'garmis January 22, 2008

"You spilled coffee on your shirt."
"Well, biffle!"
"You don't have a date for prom?"
"No, I've been biffled!"
"Well, biffle!"
"You don't have a date for prom?"
"No, I've been biffled!"
by Kitty11 May 25, 2008

A member of the other romantic interest that you are very close with. Your best friend that you would never consider dating. The two may seen like a couple but they are just biffles
by The dancing ninja October 28, 2015
