Loaf Share definition Flag 1. The Best. 2. Sex. 1. -Who's Loaf? -He's the best.2. -Yeast is constantly having sex. In your bread. Loaf = Sex. Loaf by Broseph Sammich May 26, 2010 0 0 Get merch Get the Loaf mug. Buy Now — $32.95 See more merch