ass-and-mouth disease

Essentially the inability to control one's bowels from both openings (mouth and anus) simultaneously. Usually brought about by the ingestion of improperly prepared food containing harmful bacteria or allergens.

Dave: Did you hear what happened to Steiny out in India?

Josh: Yeah, he shat and barfed all over his bed after he caught ass-and-mouth disease from that street vendor!

by PME InfoSource December 26, 2008

CHD (Chronic Hand Disease)

it is when a guy decides he doesn't want to text you or call you, yet he calls and texts everyone else who isn't important this can pertain to woman as well. Usually these people are on some level of the Heffadonkis spectrum. They usually know you want to hear from them and you care and deliberately ignores you and does not call you or try to contact you like their is something wrong with their fingers.

Why didn't you call me last night? I was waiting and you said you were going to call me back. I was talking to my friend Patrice and then I didn't feel like it. What did you do after that? I went on facebook. You know that just shows you got CHD (Chronic Hand Disease)!

by UloPeach February 19, 2010

mad cow disease

something PETA planted in our cattle in an effort to turn everyone to vegatarians/vegans

damn PETA now they are trying to kill meat eaters with mad cow disease

by kick petas ass January 3, 2004

dirty dick disease

It is what you get if you have slept with over 30 women.DDD

Man i bet that guy has a bad case of the Dirty Dick Disease.
My friend has some bad DDD

by C MART December 28, 2005

Ring Disease

A hot young woman who is unfortunately married.

Although Les has the Hots for Lisa she has Ring Disease.

by Les B. Labbauf June 4, 2004

Fortnite Disease

Common within development studios, Fortnite Disease attributes to feeling inferior and struggling to become more like Epic Games due to their frequent (usually weekly) updates, active and supportive community which gives feedback, and large community. This causes devs to feel like they have to work a lot harder to even come close to competing with a game as large as Fortnite.

Person 1: Fortnite Disease is starting to become really apparent within game devs lately.
Person 2: I know, right? Honestly, they should take their time with updates so they don't fuck up the community more than normal.

by pinjer October 14, 2018

Trump Disease

Mesothelioma, in the Trump era.

This deadly form of cancer has been renamed to Trump Disease in light of the president's lifting of the ban on asbestos in manufacturing, which will undoubtedly lead to a rise in cases of mesoth - ahem - Trump Disease in the coming years.

John: Hey, man, you okay? You been coughing a lot lately.

Zion: Nah, man. I just got back from the doctor. It's Trump Disease.

John: Fuuuuck.

by spreadthebird August 10, 2018