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When a person ingests a said quantity of opiates or uppers and is sent into a mania of sudden movements such as beating on their thighs or cleaning vigorously by effect of the drug. Or the act of doing opiates and uppers together otherwise known as speedballing.
Rumpus was doing the hambone after that bump and started cleaning the kitchen.
Hambone by Megaseth May 7, 2010
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Hambonersteen 

Of or relating to an instance or situation in which one is screwed over or fucked up. The word is applicable to many situations including instances of late night escapades involving women or alcohol.
After Jim and John shotgunned twenty beers and chugged a fifth, they were hambonersteen and could not find their way back to the hotel.

Those guys were really good at beer pong, we got hambonersteened and lost by eight cups.
Hambonersteen by Gek Nation April 11, 2011

The Hambone 

The nickname for Hammond, IN; a city that touches southeast corridor of Chicaho, IL.
What part of Chicago are you from? Oh, you know I'm the hambone.
The Hambone by Northwest Drilliana September 12, 2016

hambones 

Large handles found on the waists of freshmen females, used as handles while conducting intercourse or for spooning. Often the cause of poor self esteem while wearing pants or skirts that are 3 times smaller than their actual waist size.
"Hey Jen, Look at that girl's hambones. It looks like a spare tire of fat around her waist."

"OMG, my hambones are soooo brused. I was conducting intercourse with Kevin last night and it was rough. I hope he hasn't found out that I'm in high school."
hambones by Chinese Tourist May 3, 2006
A person, usually male, who extreamly dedicated to fantasy sports to the point of degenerate level and is also extreamly successful in the afore mentioned fantasy endeavors.
Timmy won the football league again? Damn - he plays like a hambone.
Hambone by ItsDJOBie July 8, 2018
Something which is wonderful in a soup and distressing in a movie. Connotation varies according to the likability of the actor being described, with William Shatner at the affectionate end of the spectrum and David Caruso at the other. See "Shatnering."
Yeah, Shatner's a hambone, but he's OUR hambone.
hambone by David Bryant May 7, 2004
to be or act in a hambone like manner
wow mike was being a major hambone in law and you class yesterday
hambone by petey green January 5, 2008