the main vein 

Penis

My bladder is so full I think its time to drain the main vein

the main vein by Xeroman January 31, 2016

Zoe main 

A person who suffers from World War II flashbacks and cancer, hated by League of Legends, and has a constant need to one shot anyone who opposes him, her or it.

Jerry: I’m a Zoe main
Tom: Don’t touch me

Zoe main by Gey for Bois December 26, 2017

Warden Main 

His name is Ian and he is probably a simp and only plays women

That player is definitely a warden main

Warden Main by ELEISHWINN September 9, 2020

ashe main

Probably the most handsom human on planet, benches at LEAST 600 pounds. 6 " 5' and plays the hero ashe in overwatch

Yo? is that Neuu on the enemy team?? hes an ashe main

ashe main by Neuu April 5, 2021

Bastion Main 

A bastion main is a guy who has no family or life and will never have such things. So, he or she picks the Overwatch character "Bastion," only to fuck with other people's lives. The bastion main can be mainly found in comp & Quick Play, it's their natual habitat.

Man, FUCK that bastion main!

Bastion Main by I_Got_Barzzzzzzzx April 10, 2017

My Main Nigga 

My Best Friend

Can also be used in context when referring to whom you often drink, smoke, or on occasion Eiffel Tower with.

Shit. There's my main nigga John. We gonna get drunk, smoke da chronic, and eiffel tower dat bitch over there. Fo free!

My Main Nigga by Tom da Bom June 15, 2008

The Main Board 

The Main Board is the most deluded place on the whole of the innernet, making it extremely amusing for both Saints fans and the rest of the world alike.

The Main Board consists of typical fred such as the one below!

Poster 1: I heard Paul Allen is coming to Saints
Poster 2: hcdajfu
Poster 3: O'RLY
Poster 4: Wow this is great we will be the best team in the world in no time!
Poster 5: We're going to be better than Pompey again!
Poster 6: That'll shut Corp Ho up!
Poster 7: w00t!
Poster 8: I'm going to take over saints.
Poster 9: Lets just focus on our next game for now!
Poster 10: OK, I think we will win!

The Main Board by wwwwwwwwww December 10, 2007