Retarded Nose Syndrome. If one has a chronically runny nose from a long-lasting illness, or just unlucky enough to have abnormally runny nose genes, they are said to have RNS. Also sometimes known as Runny Nose Syndrome, for those easily offended.
Heather: Why do you have such a huge pile of nasty tissues by your desk?
Me: I have an acute case of RNS, once it starts it takes hours to die down!
Heather: Real nice.
Me: I have an acute case of RNS, once it starts it takes hours to die down!
Heather: Real nice.
by David J. Hansen April 26, 2009

by MICHELLE April 7, 2005

Text speech for "Real Nigga Shit".
by Churchill291 April 11, 2016

by JoE March 30, 2003

by L.4.Life November 20, 2016

Derived from RNG or Random Number Generator. Typically used in video games due to the luck of a random number generator being represented as a Miracle or Divine intervention and thus the character of RN Jesus is prayed to or thanked for Luck. Most situations where RN Jesus is invoked involve games with Random Criticals like Fire Emblem and Team Fortress 2.
"I have a 1% chance of getting a Critical Hit and RN Jesus blessed me." Then later... "Why RN Jesus, why? I had a 99% chance of hitting that!"
by Voreala July 21, 2016
