Knowingly or Unknowingly smoking a cigarette laced with the drug 'Spice'.

Small amounts of this drug can be mixed with tobacco, often resulting in dramatic effects.
I feel weird, think I've been 'Spiced'!
by Gregstarandgoff December 11, 2018
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bf "I learned something new on the Spice channel."
gf "really show me..."
by mr. filler July 15, 2004
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2-CI, aka 2,5-dimethoxy-4-iodophenethylamine, a short acting synthetic psychedellic compound. Can be taken orally or snorted.

Often confused with mescaline, therefore it is sometimes refered to as "synthetic mescaline".

the name comes from the fictional conciousness expanding drug "spice" found in the book Dune, by Frank Herbert and the Star Wars films.
"They have been tripping on the spice all night."
by they speak to me in dreams October 17, 2005
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The plural of spouse.
When talking to my friend I ask, "should our spice come along, or should we leave them at home to do dishes?"
by throwhimdownthewell October 6, 2006
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A synonym of cool, lit. When something’s spicy (not flavor)
That’s spiced. Eso es especiado. His shoes are spiced.
by Kalin808 November 2, 2018
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a subtle blend of seasonings and spices;

also used to describe an attractive person
rub the spicing on the meats

Wooohoo! Spicing!!!
by Broke D September 12, 2019
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Used to indicate anger; "spicey" can mean "angry".
Joe "What's the matter, you feelin' spicey?"

Barry "Yeah, someone just keyed my car."

- Or -

Joe "I've got the ill spice, I got pulled over today."
by Neo June 15, 2003
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