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The Motherload 

A large quantity of something thats awesome!
Damn, youve got 50 Bud lights in your fridge.
Yeah dude its the Motherload.
The Motherload by Nimsz January 30, 2010

Motherload

1) The best online game ever. In this game you are given a Mining Pod and you dig for minerals on mars.

In this game you can get various upgrades such as a bigger fuel tank, a better Drill, a better Radiator, etc. You can also buy dynamite, C4, excess fuel tanks, etc.

You can play this game at Xgenstudios

2) A large quantity of something such as money.
1) Me: Have you played Motherload?
Loser: OMG THAT GAME SUX! IF YEW PLAI IT YEW SUX!

*one minute second later someone finds the loser with a kife jammed in back*

2) I hit the motherload in Vegas!!!
Motherload by Grade-A April 6, 2005

motherlode 

Noun: The main vein an IV drug user hits when injecting drugs. It tends to produce the bonanza of highs; notoriously a hot spot for abscesses, often prone to collapsing or clotting, frequently located on inner arm (inside of elbow), in the groin, or in the neck. Be careful, because hitting the motherlode too much can make it unusable.
Robert, AKA Mr. Harm Reduction: You know Kevin, if you are going to shoot up glass, you should really try to switch up veins. You gotta give those things a break. That shit is fucked. *points to Kevin’s swollen nasty inner arm*. At least switch to cocaine or something... not heroin that’s lethal... you know what why don’t you just smoke crack?

Kevin, AKA Mr. Meth: FUCK Bob, you’re such a cocksucker. *anxiously tries to find a vein on hand for 30 seconds* Nah fuck this shit, I’ma hit that godamn motherlode; I’m tweaking so bad right now, if I don’t get a one hit wonder I’ll probably bug out. This is gonna be a bellringer, dude. *flails around like a lunatic trying to set it up*

Jane, AKA Ms. Sobriety Girl: *stares* He needs to take a couple Xanax bars, eat a sandwich and take a 48 hour nap for fuck’s sake.

Bob, AKA Mr. Harm Reduction: Yeahhh um *watches Kevin run in a circle chasing the shadow people* Yeah..... He might need to go back to rehab.
motherlode by SativaQueen March 3, 2019

Michigan Motherload 

An abnormal amount of ejaculate. Refers to the Great Lakes surrounding Michigan, and that the amount of ejacualte can be compared to the water in said Lakes. For obvious reasons, this should only be used involving EXTREME amounts of ejaculate. Otherwise, refer to Salt Lake Salt Bath.
Man, that was one Michigan Motherload I fired off there!

mothertoad

Used by scammers when enraged.
Does +15 mental damage if the victim has high cognitive abilities.
Can be used against itself if the victim has bad hearing.
He is a mothertoad! Daniel is a mothertoad! - Adam
mothertoad by Niagaranobs June 21, 2023

The motherload 

Born in the call of duty series, the motherload is when a single player finds more then 3 enemy team mates all together at once. Throughout history, the motherload was a common way to describe finding a very large amount of something valuable. Motherloads are most commonly found in cod multiplayer online game types such as; team deathmatch, headquarters, domination, etc.
syco - omg dude i found the baby, that means the motherload can't be far behind!

el rey -omg there they are, there's 5 of them, i've found the motherloadddd!

*gets a multi-kill*