Double Down Syndrome

The listless state of consciousness experienced after eating a KFC Double Down sandwich.

Brad: "Why does Ken look like he's about to collapse?"

Trevor: "Judging by the lunch we just ate, it is my determination that Ken is suffering from Double Down Syndrome."

by Lamb Lamb April 21, 2010

Fortnite Down Syndrome

A person who cannot get off fortnite. If they do they will crave it until they get back on. Some call it Fortnite down syndrome, others call it being 9 years old. What ever It is I have it.

Bro my little brother wont get off fortnite!
Yeah I saw, I think he has Fortnite down syndrome!

by WiiSports April 26, 2020

Retarded Harry Potter with Down Syndrome

A goofy kid who resides in Basking Ridge, often found meowing after two sips of beer.

That Retarded Harry Potter with Down Syndrome was meowing outside my house last night!

by lsutigers1128 May 3, 2010

down syndrome

you guys are all assholes sayin that stuff bout down syndrome....down syndrome is a form of mental retardation that causes you to learn slower and usually some of your physical features are different. They can be rather high functioning or non.

people with down syndrome can be very nice.

by Anonymous June 15, 2004

Down syndrome

A condition where you have an extra chromosome. The normal amount of chromosomes is 46, and with Down syndrome you have 47.

Diego Reyes has mad Down syndrome.

by Are you Tweakin May 29, 2016

Upside-down syndrome

When some one is acting like and autisticcancer ball

Tom hanks has depression and upside-down syndrome

by Footlettuce January 24, 2019

Three-Nil Down Syndrome

The sudden onset of fucktardery amongst your FIFA team when you go three-nil down.

Symptoms include: The inability to pass to anyone, inability to tackle, sudden urges to set up the opposition for sitters and in bad cases, the complete loss of the ability to retain possession.

"How have you just scored with Stuart Downing?"

"You were 3-0 down, mate. There's no way your defenders could tackle a player of Stuart Downing's capability once Three-Nil Down Syndrome had kicked in".

by SERGATRON vs. FernanGOAL October 31, 2012