A person addicted to some type of speed whose favorite hobbies include taking things apart beyond recognition, sitting by the backdoor with a large knife, 'dieting', watching American Idol, and staying up for up to 2 weeks strait. They can some times be dangerous, but are usually a lot of fun.
Yea, that fucking tweeker was about to stab me when I walked through the door, but then she realized who I was! After I watched American Idol with her she gave me her TV to go across town and get her some more crystal. Yea, she's been looking really skinny...
by Cali February 10, 2004
Get the tweeker mug.A person typically and habitually under the influence of cocaine, methamphetamine, diacetylmorphine, and any other tweaker choice you could think of.
Bob: Hey Jimmy see that guy over there?
Jimmy: Yeah man, he's acting pretty weird.
Bob: Eh, must be tweaked out or something .
Jimmy: On the real lets keep movin.
Jimmy: Yeah man, he's acting pretty weird.
Bob: Eh, must be tweaked out or something .
Jimmy: On the real lets keep movin.
by Burberry Hilfiger January 16, 2016
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Tweeker
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A girl that likes methamphetamines and sex so much that she spends the majority of her time in front of the mirror applying layer after layer of makeup so she will look good for sex.
by Jamie Pheloney April 9, 2005
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