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fo shizzle my nizzle 

for sure my nigga - derived from our friend william shakespeare
"fo shizzle or no fo shizzle that is the quizzle my african american bizzle"

fo shizzle my nizzle 

"I concur whole-heartedly, my African-American brother"
Hello, wouldn't it be great to go for a drive in my 1964 Impala, while drinking a 24 oz alcoholic beverage, to attempt to copulate with members of the opposite sex?

"I concur whole-heartedly, my African-American brother"

Fo' Shizzle My Nizzle 

An abbreviation of the Latin phrase, "For Shegro, My Negro."

Although modern linguists are unclear on the definition of the word 'Shegro', it is widely believed that it is related to the worship of the Roman Goddess Goddamnatsonehugebitchia. Certain daily activities were thought to cause the goddess to increase further in size; therefore, these activities were conducted 'for shegro.'
"Yo, you wanna go to the liquor store for a fifth of cat piss?"
"Fo' shizzle my nizzle!"

(Or, from the ancient Latin)

"Come hither, O Dumbassitus Putridus! Let us away to the market of bottled lusciousness!"
"For shegro, my negro!"

for shizzle my nizzle 

man1: that is dumb
man2: for shizzle my nizzle
for shizzle my nizzle by Logz0r March 15, 2004

Fo Shizzle My Nizzle Bo Dizzle 

A phrase used to agree with something.
Izzy: Do you agree that Mountain Dew is the greatest soda ever created?

Stossel: Fo shizzle my nizzle bo dizzle!

fa shizzle my nizzle 

To say something is definite. For sure my nigga.
1 guy: You goin' to that club tonight G?
2 guy: Fa shizzle my nizzle, I'll be hittin that spot round 11.