iss

iss is slang for in school suspension.

Brandon: “Hey want to eat with us during lunch?”
Cameron: “Sorry I can’t I have an iss.”

by DeeplyDefined May 20, 2018

iss

to kiss with no affection towards the person

Me and Drew L. just had an awesome iss!

by lolo mill November 5, 2009

iss

Iss: derivitive of the contraction It's

iss alrightkidd, dont worry bout it

by Mercutio May 13, 2005

Isse

Isse is the sexy guy alive, he'll steal your girl and look good doing it. Watch out felllas his shiny smile will blind you and his caring personality tops it all off.

Yo look over there that guys chatting up my girl he's such an Isse

by Badbihinla April 15, 2017

iss

The new lol, it means I slightly smiled, which is exactly what you do.

A: Guess what I just saw brain cheese, it tasted good.
B: iss

by BilloJill September 25, 2006

Iss Afto

Mrs. Afton.....your a FNaF fan?? ( ͡° ͜ʖ ͡°)

Hey guys look! It’s William’s ex/wife! Iss Afto

by Ilikecheeseheheheheheh May 20, 2021

OMG ISS

When somebody says something really stupid,OMG ISS is what you should reply with. It stands for OH MY GOD. I'M SO SURE!

Drunk guy at the bar "Will you pleeaaasse take me home with you?"
Michelle "OMG ISS!"

by Sosure March 24, 2010