A Skeezer(not a Skeezo) is a person whom is refered to as a hoe, who wants to have sex for the the pleasure of it, a fat ol' ugly ass bitch, that wants some attenchun, or in short.....a neighborhood hoe, that the whole family could enjoy for just a buck, or two.
"Damn son, you see dat skeezer right thurr? damn boi, A,yo! she's the AIDS virus with legs, dawg! check dat shit out"