The "mid life crisis" you might get when turning 16, or another young age. Happens when you realize you are no longer Peter Pan, defender of adolescent bliss and are at some point in your life going to have to live all alone.
Girl: Excited about your birthday this sunday?
Guy: Not really.. I'm actually in a bit of a pre-life crisis right now.
Overachieving-ass dweebs (like Hermione) that are in all your biology and chemistry classes. They let everyone around them known that they are pre-med either directly or indirectly through their obnoxious behaviors (including, but not limited to: asking questions about how the material is relevant to the medical field, whether or not the professor has finished writing them a recommendation letter, and boasting about their shadowing experiences). An important thing to note is that not all pre-med hermione's are actually smart, but pretend to be.
Pre-med Hermione: "I'm getting my surgery next week. But I'm not worried; I've seen the procedure done like a hundred times."
Pre-med Hermione: "I can't wait to be a doc. I'm gonna be all like "Open your mouth, and say 'Ah'""
Pre-med Hermione: "Those pills are really bad for you. I would know. I'm pre-med."