Isolation

A drinking game perfected in the East Coast of Canada that combines solitary confinement with liquor. Every participant must drink a handle of hard liquor in 45 minutes while isolated in their own personal room or confined space without any human interaction or communication. (Including cell phones, television, or even talking). The last person to finish their handle loses the game.

"We played Isolation last night.... It got fucking sloppy"

by dc15 October 25, 2009

isopod

a crustacean creature that lives in the sea or on land.
Also used as a Alt-Right hate symbol to show hate for niggers, kikes, spics, and fags

Anon 1: did you see CNN it was saying that an Isopod is used as a Hate symbol online.
Anon 2: well thats what the Soyboy libtard media wants you to believe right, then I Guess its true. #Isopodgang

by OPtheSloth January 15, 2018

isotope

Lighter and heavier versions of the same thing, (but usually in reference to atoms)

Bud and Bud Lite are "isotopes" of Bud. When you gain weight, you just become an "isotope" of your former self.

by 387mqr October 9, 2008

H is O

When you hear this...you better look out! Someone is bringing the heat, maybe even glen frye.

'come in here with that kinda attitude, and the H is O!'

by HM December 17, 2003

isoholes

A group of people similar to, alike, equal to and identical to assholes.

I visited France once in 1991, it is populated with isoholes.

by harry flashman August 3, 2003

isotired

The origins of this word goes back to an episode of Comedy Central's South Park. In the episode depicting tolerance in the aptly named Museum of Tolerance, the boys find what appears to be a sterotypical Mexican sleeping on the job in wax form. However, they accidentally rouse him. This is where the word is born. He says, "Isotired buay". It was started by I in its informal manner when I said my friend was always sotired. Since then, anyone across the whole state of Texas, Mexico, and the Continental USA uses this term.

Guy: "Hey man, you want to go see a movie tonight?"
Guy 2: "Nah man, isotired..."

by Chile3000 September 22, 2005

isopod hour

An hour of isopod love

when its real isopod hour

by Geo444 February 10, 2018