GUI 

The offense known as gmailing under the influence.

When I woke up this morning, there was an angry response in my inbox from my ex. I sent him a misspelled email when i was blackout- don't know how I made it past those math problems. I totally GUI'ed.

emailer: I misdf youuu soooooo muuuu7u777uuuuchy!! comevis8t meEEE! yourluv, vrovy
emailee: Someone give that bitch a GUI.

GUI by thereceiver February 25, 2009

GUI 

Gay Underage Intercourse

Damn DePaul students really be participating in GUI

GUI by Bereket T October 7, 2019

Gui 

A handsome hunk of a man, who is gay

Girl 1: Look it´s Gui
Girl 2: I WANNA TOUCH HIM
Guy: Back off he is MINE!!

Gui by SandHobgoblin November 20, 2014

Gui 

A person that is addicted to anything it touches.

He touched a halo 3 game now hes gui.

Gui by gui14235678978678 December 24, 2008

gui 

What happens when chewing gum gets stuck on your keyboard.

"What this goei?"

gui by Stefan Degeest May 18, 2003

gui 

a synonym for pussy,vagina, vaginal cavity, shit like that, can be used by anyone( but only sounds good in a black mans mouth). this version of the word was founded in technology class:

can also be a sub for bitch, broad, redbone, bobblehead, shit like that.

teacher: alright class GUI: what does it mean.
nigga: yo dats wat i got from ya momz:
other nigga: yea well ya ass better be happy dat ya moms GUI is nasty ass hell,

gui by yung chizzle June 13, 2007

Gui 

No sense of humor, and smells bad.

that neckbeard is a total gui.

Gui by poisinfrog August 2, 2017