Sup Muff? is a phrase that can be used in a variety of ways. It can be used to express pleasure, pain, confusion, elation, sadness, and a wide range of emotions. The phrase is typical among High School students in the south east Pennsylvania and Central New Jersey area.
Examples:
1) JMIRA: Sup Muff? What's up?
2) DR: Oh! Sup Muff! Oh! Shit!
3) SCHAFLE: SUP MUFF!!! FUCK
1) JMIRA: Sup Muff? What's up?
2) DR: Oh! Sup Muff! Oh! Shit!
3) SCHAFLE: SUP MUFF!!! FUCK
by Mike Canavan May 10, 2006

A phrase you say to be indicative of a flirtatious vibe between two people or outright expose a developing couple for the relationship that they share.
David and Daniel are hanging out having a conversation.
Vicky suddenly shows up and approaches them two.
Vicky gives Daniel a hug and starts flirting.
David: Sup tho Daniel. Sup tho Vicky. *Laughs*
Daniel and Vicky: *Clueless to what David just said*
Vicky suddenly shows up and approaches them two.
Vicky gives Daniel a hug and starts flirting.
David: Sup tho Daniel. Sup tho Vicky. *Laughs*
Daniel and Vicky: *Clueless to what David just said*
by Sup Tho Guys September 9, 2010

by Issa and bh cole April 28, 2006

Used to initiate conversation with your close friends. Usually followed by "BITCH" or something of the likes, it is a very useable phrase.
by not your mum October 11, 2006

A question to be yelled out car windows at passing girls on the street in an attempt to irritate and/or insult them. May be used as a drive by insult.
by Drive By Insulter December 12, 2009

When you and someone else are in an argument, and the other person says they are better than you (scored more goals in a game, got a better grade, etc.) and you tell them you got the better grade or what not, adding on the end, "sup dude?" in a nonchalant manner, just to rub it in.
Jake- "Hey man, how'd you do on the test last week?"
Mike- "I got a 95, how'd you do?"
Jake- "I got a 98, sup dude?"
Mike- "I got a 95, how'd you do?"
Jake- "I got a 98, sup dude?"
by Supdude93 April 21, 2009
