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Avoid Pi Like the Plague

An ill-advised mantra math-anxious folks unquestionably take to heart on hearing it from negative or unhelpful people, who are only contaminating the minds of their listeners with fake mathematical information.
To tell someone to avoid pi like the plague is like telling them that π is a rational number because it can be expressed as the ratio of a circle’s circumference to its diameter.
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Black Plague 

The sickness provoked by a startling, unprepared for viral attack by the name of "Rebecca Black." Symptoms include beign followed by 30-year old black men while sitting in your school bus and having to make the unorthodox decision of trying to decide which seat to sit in.
Aw, man. I was only trying to youtube Charlie Sheen and i accidently stumbled upon the black plague!
Black Plague by mumbojumboWHAM April 4, 2011

Hippy Death Plague

A disease attributed to virus, that is generally caused by smoking weed or marijuanna when one is even slightly ill.

The smoking greatly exascerbates the illness and adds to it's duration. Any smoking before your system is purged, will only strengthen the Hippy Death Plague and worsen your symptoms.
When I was smoking at Purchase, trying to lessen a headache and a slight tickling in the back of my throat, I unwittingly opened the door to the full-blown Hippy Death Plague.

Dude, you shouldn't be smoking if you're sick. Don't you know about the Hippy Death Plague?
Hippy Death Plague by Seffbasilisk October 11, 2009

person plague 

When your doing "Randoms" (Constantly pressing the shuffle button for funny definitions) on Urban Dictionary and you keep getting peoples' fucking retarded names.
"Terry, Who gives a fuck about Terry? I'm getting person plagued."

Black Plague 

Any girl that has had/have every STD
Black Plague by Octapussay December 4, 2016

thot plague

The thot plague is a evil disease that can devour anyone and turn them from a innocent person into a thot.
My school is being infected by the thot plague

Sarah has been infested by the thot plague
thot plague by Dãddy Reyn October 13, 2018

Bubonic plague 

What people treat the coronavirus like.
You don't see dead bodies laying in the street, at least not yet, so is the pestilence called the coronavirus anything like the bubonic plague?