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Pre-nut Syndrome 

1) The phenomenon wherein a man who has gone without sexual relations for a period of time experiences a decrease in selectivity with respect to those persons that he seeks said relations with. As the period of time in which said man's sexual relations are in absentia increases, there is a direct inverse relationship with said selectivity. For as long as the `drought' persists, the selectivity will decrease exponentially.
During a consultation with his urologist, Cicero expressed a serious interest in draining his balls in Miss Mary Jay Rottencrotch's STD petri dish. Since ions had gone by since Cicero had last sunk his Italian sausage into a quality hole, the doctor diagnosed Cicero with a severe case of Pre-nut Syndrome.
Pre-nut Syndrome by duchebag81 July 24, 2010

I.D.G.A.F syndrome 

short for " i don't give a fuck" which is a very contagious disease causing massive amounts of random anger induced outbursts, spontaneous lack of interest in just about everything, increased will to start and or instigate fights with no clear motive. WARNING: MASSIVE AMOUNTS OF BOREDOM WILL TRIGGER THE I.D.G.A.F
Terry:what the hell is Jason's problem, he just cursed out the teacher and slapped his own girl in the mouth.

Brian: He just caught the "I.D.G.A.F syndrome" man!, watch out before he does some more random shit!!

John Gomez Syndrome 

An incredibly horrible condition in which you wear suits, discuss politics, and take constant ridicule for being John Gomez. In fact, you probably broke your leg sliding into a fucking base during baseball, and ended up on crutches for all of middle school for being such a fuck-up. John Gomez Syndrome is the equivalent of cancer, but to a more deadly degree.
Dude, why the fuck are you wearing a suit and talking politics?
I've been diagnosed with John Gomez Syndrome
That sucks
John Gomez Syndrome by RoxerMan October 24, 2014

Atlas Syndrome 

The condition of dealing with constant burden; Comes from Atlas, the titan in Grekk mythology who literally carried the world on his shoulders.
I tried my best to get Jerry out of the house and distract him from getting fired and losing his girlfriend, but he was too preoccupied with his Atlas Syndrome.
Atlas Syndrome by Curtis Meyer November 14, 2009

Google Syndrome 

When you suddenly think of some completely random question that has to be looked up on Google and answered right at that very moment.
This syndrome usually leads to the more serious illness of Google Search Syndrome or in more serious cases, Youtube Syndrome.
Jill : "... I wonder how much the average male platypus weighs..." *leaves to go on the computer*
Alex : "Ugh. You have Google Syndrome again!"
FIVE HOURS LATER.
Jill : "Alex, did you know that the average human accidentally eats 8 spiders in their life?"
Alex : "Ugggh."
9 HOURS LATER.
Jill : "Hahahaha! Oh, Fred! He's so funny. Can we go buy some helium to talk like him?"
Alex : "...."

RIT Syndrome 

An affliction that someone who attends the Rochester Institute of Technology (RIT) suffers from. It tends to occur when they take a required gym class and automatically become the greatest at the topic of the course. It also occurs when the tremendous amount of knowledge and power that an RIT education provides overtakes everything else they have ever learned and they instantly become the smartest person ever at everything.
My brother suffered bad RIT Syndrome when he took a gym class in kick-boxing and proceeded to try kicking me in the face every time he saw me for the next 2 years.

My office-mate has horrible RIT Syndrome. He can hardly talk about anything other than how much better RIT is than every other school.
RIT Syndrome by CMIF LM February 28, 2012