the state of mind when using methamphetamines that the user cannot stop doing an activity and has been up for days.
by Tweeker July 17, 2003

by chillcat May 29, 2003

the nervous ticks or twitching one experiances as they come down from a crystal methamphetamine binge.
by a former tweeker November 28, 2003

"Dude, no one is talking about you so stop tweeking."
"Just because you're alone it doesn't mean someone is watching you, so stop tweeking."
"Just because you're alone it doesn't mean someone is watching you, so stop tweeking."
by Melisha July 5, 2005

by URBAN HOODS January 19, 2015
