Wise Mule Syndrome: A condition in which one cannot stop being a smart ass, regardless of race, culture, situation, alcoholic content, or media. While the contemporary social view is that clinical sufferers of this condition are choosing to be a smart ass, it is in fact, medically impossible for them not to be without the proper medication. If you encounter someone who has been diagnosed with WMS the proper response is to either back away slowly, or laugh at everything they say as the are inwardly sensitive and self-conscious. And awesome.
"I apologize for equating your bust to water balloons during my speech at your wedding reception last night. I suffer from WMS."
by iolympian February 16, 2014

by jarheadfor4 March 24, 2005

by salakommander December 11, 2006

by blankman 1 October 15, 2008

by Randomuser6352 May 5, 2020

Acronym for Window Manager. Manages windows in the X window system(commonly called X11, X11R6, or just X)
by Anonymous July 14, 2003

by trcagl May 10, 2011
