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Abbreviation for "Significant Other". The gender-neutral way to refer to someone's boy/girlfriend.
I'm having a party at my place. Bring your S.O.!
S.O. by The Grammar Nazi November 10, 2001
Related Words
Hey, stop macking your S.O. and go home.
S.O. by unicore November 19, 2006
man I hate playing those S.O. guys they really trashed us in clan wars!

wow can you believe that %*#**in S.O. clan beat us like that?
S.O. by SO_nutcase911 January 7, 2014
"Dude, this Natasha girl is hot!"

"Right? RIGHT?"

"By the way, what's her S.O?"

"I hate to break it to you, man, but... I think she's gay."

"Gooooddddaammit! Actually, wait... that's pretty hot."
S.O by Danielakojas February 18, 2019
An acronym for the derogatory term, saucey orifice, used instead of "significant other" to designate a woman that's kept around for physical pleasure. Can be used cladestinely in front of said S.O. when speaking to a friend who is "in the know". Said S.O. is lulled into a false sense of security thinking that they are your "significant other". (Only heterosexual use allowed as any other orifice is only saucey after the fact.)
Bob: Albert, just who is this engaing creature?

Albert: Oh, this is my S.O., Fillmein. Fillmein this is Albert. (Wink....wink)
S.O. by BigBlackBlick February 3, 2010