The act of blowing on a male's penis without actually giving a blow job.
Jane and Brad wanted to wait for the right moment before they started to have oral sex. In the mean time Jane would give Brad blowies by blowing on Brad's erect penis.
When somebody knows their not going to make it in life, but try's anyway only to fail miserabley like the universe intended them too. When somebody deserves the fame but god doesn't respect them so he takes "blowie" out of the loop no matter what he does.
Blowie: "oh man im gonna try out for your football team", Coach: " Pssh, that blowie will never get on the team"