An insult used to insinuate that an opinion does not matter or hold credence.

The term is derived from the phrase "my two cents" in an attempt to use sarcasm and irony to convey the lack of personal interest the speaker of the word holds for another's opinion.
"Nobody respects your twain garbage"

"Thank you for sharing your twain *sarcasm*, now I am going to go and do something that is useful"

"Keep your twain to yourself"
by scraz51_again September 10, 2009
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The length of your buttcrack spanning from your asshole to the small of your back.
My Twain was chaffed because my thong underwear was too small.
by Thomas M. Pace July 23, 2008
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To publish under a pseudonym like Mark Twain.
I am totally Twaining this tumblr page, it is way to personal.
by Samuel Langhorne Clemens March 26, 2012
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The rather obvious portmanteaus of brain + Twitter. To communicate directly via the brain's electrical impulses through Twitter. Reference:
Brain-Twitter project offers hope to paralyzed .
He can't phone me because he's quadriplegic, so he's twaining me.
by xrd1 April 23, 2009
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A Portmanteau of the words Two and Pain, usually meaning a body part was painfully snapped or split into more than one piece.
by Dinjoralo May 24, 2011
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A man who came up with approximately 50% of all quotes used today.
"Let there be light"

-God famously quoting Mark Twain
by JJHOUSEE September 12, 2010
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D-Twain is a legendary Gangsta Rapper. His real name is Suren de Saram. He is the drummer in the band 'Bombay Bicycle Club'. The internet exploded after D-Twain's single reached 10 000 000 000 sales and was Zane Lowe's record of the week.
WHERE IS MY FUCKING LATTE, MAN
~ D-Twain
by FuryLullaby October 27, 2011
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