Duff

to throw a severe beating to another person or group. Used with mal intent or to beat the ass's of.

"If you don't shut the fuck up, i'm gunna duff your dumb ass"

by DamionFK December 3, 2006

duff

the type of beer Homer Simpson drinks

pass me another Duff Mo

by :o) April 25, 2003

duff

Designated Ugly Fat Friend

Two hot chicks at a bar will have a really nasty fat ugly bitch hanging out with them, refered to as a "DUFF".

"Wow that fat DUFF is hanging out with those two attractive ladies, too bad."

by Cobra January 26, 2003

DUFF

Designated, Ugly, Fat, Friend - this is a person in a friend group who is there to make everyone else look good.

girl 1: she doesn’t fit in with that friend group!
girl 2: yeah because she’s the duff!

by Thatsmarthighschoolgal November 24, 2019

DUFF

Designated Ugly Fat Friend

Doesn't necessarily have to be fat, or ugly, but is less attractive than the friends she/he hangs out with. Men/woman usually befriend a duff to get closer to his/her friends. A duff mainly gets used for info and or help, and is often lead on mistakenly or purposely. Do not allow the duff to realize who he/she is and why you are using them, because you will 100% lose them as a friend. If you even care.

Guy 1: "Hey see those hot chicks? Except that one, she's so the duff."
Guy 2: "Yah man? Let's try to be her friend, maybe get some info on her hot friends"
Guy 1: "let's do it!"

by That1DUFF November 20, 2015

duff

Designated Ugly Fat Friend.

That 3rd girl is definitely the duff of the group.

by G January 2, 2004

Duff

A real term used in the heydays of Cocaine frenzy, 70s, 80s. Duff refers to that portion of your cocaine that consists of powder only, usually full of cut or anything else but real cocaine.

Shit, I won't buy from that dude again, this is all duff.

by Gojai August 30, 2017