1.Used to categorize an affliction that turns a normal woman into a mountainous, sloppy looking woman with a snub button nose and a haircut that was crafted with a lawnmower. Usu. gotten by having low self esteem, recreational drug use, poor diet, and lack of intellectual stimulus.
2.Any other similarly or un-similarly described fatter female afflicted with this ailment.
Ex1: Friend1-" What in the hellhappened to her?!"
Friend 2-"You didn't hear? S'shame. She developed Mad Cow Disease..."
Friend-1 "Fuck!"
Someone being of or like a really mean person, specifically and cranky music teacher. They tend to say maaaahhhhh when they are angry. You can use it as any part of speech.