1.Used to categorize an affliction that turns a normal woman into a mountainous, sloppy looking woman with a snub button nose and a haircut that was crafted with a lawnmower. Usu. gotten by having low self esteem, recreational drug use, poor diet, and lack of intellectual stimulus.
2.Any other similarly or un-similarly described fatter female afflicted with this ailment.
Ex1: Friend1-" What in the hell happened to her?!"
Friend 2-"You didn't hear? S'shame. She developed Mad Cow Disease..."
Friend-1 "Fuck!"
Someone being of or like a really mean person, specifically and cranky music teacher. They tend to say maaaahhhhh when they are angry. You can use it as any part of speech.
The teacher was totally being all mad cow disease last night. She was all " maaahhhhh"