eightball Share definition Flag A 40 Oz. bottle of Old English malt liquor. Sometimes misspelled as eighball. The boys were hanging around downtown behind the laundry mat, talking about women they may or may not have screwed and drinking eightballs. eightball by Yoboface Killa August 14, 2004 0 0 Get merch Get the eightball mug. Buy Now — $32.95 See more merch