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Lose one's shit 

To lose control of one's behaviour, to the point of verbal and/or physical aggression.
We've had to deal with quarantine protocols for a week and all residents have had to remain in their suites with no visitors. Some of the residents that have more advanced Dementia are losing their shit. They're becoming physically aggressive. But to lose one's shit comes more easily with quarantine than one would otherwise think
Lose one's shit by chrisssy226 October 25, 2020
Related Words

Lose Larqueef 

That one friend who talks the most shit when playing basketball despite the fact that they don't have an ounce of skill or athleticism in their entire blood line.
Lose Larqueef: "I want him."

*Proceeds to break his own ankles and fall over like a complete fucking retard*
Lose Larqueef by Larqueef the cuck February 26, 2022

Lose the battle 

When you have to take a shit really bad but nowhere near a toilet so you have to focus on not shitting yourself
Yo bro you good? Nah man if I don’t get home quick enough ima lose the battle
Lose the battle by Atwerkingfetus September 9, 2022

lose weight 

v. diet that consists in dropping an enormous amount of ass matter from one's 2 hole; vastly more effective dieting strategy than any proposed by the money hungry Jenny Craig or fitness guru Jane Fonda.
Dan: Where you goin', man?
Don: To lose some weight.
lose weight by Dr. Metal August 11, 2003

Lose My Breath

1.When a woman wants a man to put it down right. 2.A man who can do it so good, that he made you lose yo breath.
Giiirl, he made me lose my breath!
Lose My Breath by Ambitious_AA January 14, 2005

lose my shit 

specific to; when you see someone you haven't seen in a while in a location or situation you wouldn't normally see them in, you get really excited because you know it's gonna be a mad day/night
Paul (high af): When I see Adam I'm gonna lose my shit!
Adam: *rocks up*
Paul: ADAMMMMMM hoLY shIT