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The nickname for new no-longer-science-fiction-related TV network Syfy that was once called the Sci-Fi Channel. Syphy is phonetically equivalent to Syfy, but expounds on the obvious connection to venereal diseases.

Syphy is used among ex-fans of the network and SF/science fiction aficionados who believe that the re-branding press release was a slap in the face for anyone who enjoys sci-fi.
There is another bad monster movie on Syphy.

TV Watcher #1: What's on Syphy tonight?
TV Watcher #2: That sounds like an STD.
TVW1: Huh. You're right, I guess it does!
Syphy by Cricket_B March 18, 2009
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syphilitic moron 

A guy who's had a portion of his brain eaten away by cock pus
Why is Al Capone fishing in his own pool... Well he's a syphilitic moron.
Related Words
A cute name for your daughter when Sophie becomes too mainstream. This spelling variation often represents a quirky, smart, loving, pretty, and very unique girl. Sophy's are often found to be irresistible and are considered a real sweetheart and cutie pie. They're quite rare to find, so if you come across one, you better hold onto her- she's seriously just that awesome. :)
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"Is your name Sophie?"
"No, it's Sophy... with a y."
"Oh, that's so cute!"

"Have you met the new girl?"
"You mean Sophy? She's so sweet!"
Sophy by Hooliganfrommars108 January 10, 2014

Flying Turbo Syphilis

Strain of syphilis that aggressively attacks members of a group or community as if if were a conscious being capable of turbo powered flight.
Action news reports that numerous Rockdale County teens have contracted a particularly nightmarish sexually transmitted disease known as Flying Turbo Syphilis.
Saphyre is an amazing girl. She is not only beautiful but kind and caring. I always feel safe when I’m in her presence. She gets flustered at the smallest things and I think it’s super cute, of course, I’d never tell her that. Her name comes from the gem ‘Sapphire,’ so it’s only fair to consider her a shinning gem. Although being easily brought aback, she’s a big flirt for absolutely no reason. She has a good sense of others emotions and tries her best to keep you happy and comfortable. When we first met I thought she was kinda awkward because she stayed stood behind another friend. But honestly, even tho she’s an introvert, she’s the best person I’ve ever met. She always listens to me and doesn’t force anything on me. If I don’t feel like talking, she understands and just stays with me until I’m okay. saphi, ily <3
Have you met saphyre?
Yeah, she’s so cute.
Saphyre by mammoney March 23, 2021

Bong Syphilis 

A condition that spreads around a collective group of stoners like wildfire. It begins when one gets infected with a particular sickness. This individual uses what is known as a 'bong' in order to enjoy his favorite enhanced vegetable product, then passes it on to his friends, thus, passing his sickness as well. Common signs that bong syphillis has occured is when one friend falls ill, followed by another friend the next week, and another and so on. It is suggested that mandatory water changing needs to be a priority of the group to ensure this does not happen. Also, when one is sick, it is only logical that he or she lets their fellow stoners know of their ailment(s) prior to engaging in a session.
Man, I was sick this week just like you were sick last week. I think it was the old bong syphilis.
Bong Syphilis by Sense21 February 23, 2007
Some guy that plays way to much skate games
Person 1- Did you watch the new Syphrus video?
Person 2- Hell yea. It was really cool when he did no ollies and beat the game
syphrus by Vadderr December 5, 2021