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400 Calories 

Supposedly making out for 20 minutes burns 400 calories.

Actually, 400 Kilocalories, but food companies thought it would be easier to denote those things we burn as calories, so what the hell. Apparently metric prefixes are fucking scary.
Chad: "Hey Lisa want to burn 400 calories?"
Lisa: "Sure Chad, but I'm not taking off my pants...yet."
{ 20 minutes later }
Chad: "Wanna burn 400 more."
Lisa: "Let's go for 2000. Take off your pants."
400 Calories by tron.von.tronicus January 8, 2008

400 and chill 

Taking 400ug LSD with your psychonaut friends and having a chill time tripping balls.
Yo bro wanna 400 and chill this weekend?
400 and chill by Profesor420 December 1, 2020

400 pound gorilla

Something that cannot be overlooked because it is so much larger and more impressive than any of the others.
When it came to rock music groups, the Rolling Stones are the 400 pound gorilla: the quinitessinally best of them all.
400 pound gorilla by Duckbutt January 7, 2007

400,000 pounds of fuel 

(falls off a cliff into a lake that smells like gas) WHOA I JUST FOUND WHAT MUST BE 400,000 POUNDS OF FUEL!
400,000 pounds of fuel by Oz March 9, 2005

400 pounds of joy 

A old hateful term for a fat girlfriend or wife that likes to have sex and is good to her man.
Did you see Jethro's girlfriend? You haven't? Well, that's 400 pounds of joy right there, boy!
400 pounds of joy by Lil' Taste October 27, 2016

400 over par 

The score of some guy who really sucks at golf.
"Hey, I really suck at golf."

"Yeah? What was your score?"

"400 over par."

"Wow. Go kill yourself, douchebag."