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Used when your plans are ruined by family obligations.
"I got screwed into some GFS"
also popular is GGFS (Gay Girl Friend Shit)
gfs by DS June 7, 2004
"I thought he'd have a larger dick, GFS"

"Turns out, she has herpes, GFS"

"I almost dropped my taco. GFS"
GFS by steampoweredgiraffegmv February 6, 2017
Global Forecast System; a weather model that predicts almost every typhoon will hit Japan as a category 5.
The GFS says the typhoon will hit Tokyo as a category 5, just like it did for all the other typhoons this year that didn't.
GFS by ThatPunnyPeep321 August 28, 2018
gfs by gfsmean December 6, 2022

National gfs day 

The day you tell her how much you appreciate her and post her all over your social media to show everyone she’s yours and yours only
Snapchat story “ she is my ride or die no one else’s I love her so much”
Everyone: “that’s so cute! National gfs day??”
National gfs day by Kati:) October 4, 2021
GFSF Karen. GFC hit her with the hard T
GFSF by Bubbaharris777 October 5, 2020