A version of the word Jesus created by Homer Simpson when he became a missionary. Used for comical purposes instead of using Jesus. Also used in games to avoid Nazi-language filters. (eg Coke Music)
Variant of Jesus, used because it's less offensive.
Originated from The Simpsons. Generally used by the general public and webcomic authors so as not to spark religious debate. It does not "use the Lord's name in vain," and gets the message across.
Tenchin: Don't struggle! They'll just bring you in deeper!
Psyguy: Save meh, Jebus!