when you have an object, or food and you mess with it to the point that it is unrecognizible as the thing it was before .
so say you have a sandwich and you prod,pick and poke at it so that it does not look like anything, that means you have marmalized the sandwich.
for a man to be cussed down in arguement by a woman or to have your Jacobs cut off.
haha, dude, you just got ripped by Holly!, she totally de-manalised you with that!
or...
oh my my god, you've got no nuts, you've been de-manalised!! unlucky.