Drunk, under the influence of alcohol. Usually to a large extent. Unable to think correctly, move correctly, or act normaly because of the influence of the alcohol.
Really, really drunk.
Often used by those that do other drugs and do not really drink as often. Getting drunk only and not mixing it with any other drugs.
Anthony: Dude!! What happened, where'd you go?!
Matt: Sorry man, I just got Treo Trashed
Anthony: Damn!! I must have been talkin' to myself for over 15 minutes.