Often used as sarcasm in response to someone who did something you didn't want doing.
Jack just cock blocked John

John: thanks a lot, Jack
by Ophooo September 17, 2013
Being super sarcastic and not thanking you for anything at all.
“Thanks a lot, Sam,” Matthew said.
by dr.c__12 July 17, 2018
A scarstic term said to an irate customer.
As the customer was leaving I said to him "Thanks a lot, Jerkass!"
by Rick James! May 19, 2007
A standard response to an awkward/inadvertently offensive/incredibly personal question.
“Listen I have a weird question and it’s not like it’s an issue but, I can’t find your balls dude. Do you have balls?”
“Now I have to worry about the size of my balls? Thanks a lot, Liz.”
by AprilUnderwater December 27, 2019
A stupid video in which a random girl "thanks" her friend or sister for her iPad not charging.
"Thanks a lot Rachel! Thanks to you, my chargers not charging..."*

Imagine in a bri'ish accent.
by S302304 November 23, 2021