thalamuspuss Share definition Flag A thalamuspuss is a gratitude so great and heartfelt that it literally breaks your brain. I got the nicest thalamuspuss from Gary after shitting in his office chair thalamuspuss by Thalamuspuss October 14, 2021 0 0 Get merch Get the thalamuspuss mug. Buy Now — $32.95 See more merch