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1)A fabricated scenario that is not what it is intended to appear as
2) A distress call that does not need to be answered
3) Anything a person with enough intelligence can see through depending on: intelligence of victim > combined intelligence of conspirators
"Help! Help! HHHEEEEEEEEEEELLLLPPPPPP!!!!!" cried the man who called the police after he was asked to locate a phone.
--setup

See Goodfellas
Setup by Yoo Si Lee October 13, 2011
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having a female on deck for a bootycall and/or train
example 1

I'll meet up with you later. I got a setup scheduled in an hour.

example 2

Bro, I got us a setup for tonight! Hop aboard the Polar Express! CHOO CHOO!
Alex: Dude, I'm having a house party this Saturday.
Brendan: Again, this has got to be your 5th party this year.
Alex: I know, it's cause my parents go out of town so much.
Brendan: Awesome, I wish I had a setup like that.
setup by benormous May 4, 2006
The part of a joke before the punchline. Is just as important as the punchline.
"Ooh! I got a good one! Why did the Emperor cross the road?"

Narrator: "Bob left for his meeting before he could hear the punchline, and the setup was orphaned in his mind."
Setup by E hates Q February 9, 2021
A tattoo or ink.
Yo, I hear Davey got a sick new setup at High Rollers.
setup by maddlater'd December 31, 2007

Setup Bitch 

A whore That plays you. Usually is with a bunch of street thugs and will take all of your money if you are slipping.
James: Bruh, I hit this girl up last night n got some.
Wayne: Wit Who?
James: This hoe named Natalia. I gave her 50$ for the whole thing.
Wayne: .....Nigga!! Natalia from Westside?
James: Yea, why you actin like that??
Wayne: Nigga you a dumbfuck!! Everybody know she a setup Bitch! Her Goons bout to come n rob yo ass.
James: Foreal!!??
Wayne: O shit.....Im outta Here!! *Runs for his life*
Gangster: Aye Bruh i hear you met my home girl........
James: Damn.... that nigga ran like a lil bitch. Who you talkin bout cuz u know i Be wit a lot of bitches.
Gangster: The bitch name Natalia.
James: yea I was wit her last night.... What about her?
Gangster: *Puts gun in James face* Give me yo money Bitch nigga!!...Yo ass should have ran but u just a stupid ass nigga.
James: I aint got no money!! *Starts crying*
Gangster: *Starts counting down* 5,4,3
James: I aint got no money!!..... Leave me alone man!!!!
Gangster: 2,1 *Shots fired, James was killed* ...... I thought yo ass said you aint got no money.....SMH.. *Gangster Takes James's Money n runs off*
Setup Bitch by King Chillen August 20, 2013

setup goodbye 

the style of goodbye where you purposely act/say something obviously stupid to end the relationship.
This chick told me she wanted to go attend a puppy pageant recently, so we went. 10 minutes in one, had enough, so i pulled a setup goodbye

told her i needed to go to the restroom, set off the fire alarm, started the whip and bolted out.
setup goodbye by Spicy fishies December 13, 2018