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The term has an origin in Scarface.

a. Something that has the quality or condition of being unsavory or tainted.

b. A slander or offence against someone who is supposed to be one of your friends.

c. A person(s) who is/are sexually contaminated, with a high likelyhood of disease. The actual having of the disease is not important, just the likelyhood.
Example A: Question: How are the wings, man? Answer: They taste three days old! They're just polluted!

Example B: "Why'd you have to cheat at cards! That's polluted!"

Example C: "Dennis was with three chicks in the past 2 days. You know he's strung out and don't wrap it up! He's polluted for sure!"
by J. Collier December 23, 2005
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