oiisu Share definition Flag Japanese slang terminology equivalent to "wassap/sup!". Commonly used in a non-formal matter. (eg: between friends) "Oiisu Ryusuke! C'mon hurry or we'll be late for the anime convention!" oiisu by fumofumo June 6, 2005 0 0 Get merch Get the oiisu mug. Buy Now — $32.95 See more merch